Longitudinal Study to Investigate Different Transcranial Electrical Stimulation
About this study
This research investigates the effect of different frequencies of tACS (0 Hz, 30 Hz, 50 Hz, 70 Hz, 90 Hz) and tRNS with cognitive exercises in a regimen protocol of 4 weeks, everyday (Monday to Friday). The study design is a longitudinal study design in which participants receive different tES randomly ordered. Treatments occur for 4 weeks, then 12 weeks of no treatment (wash-out period), repeated for each tES treatment type. Participants have the option of having their choice of music in the background while they perform cognitive exercises.
- Condition
- Dementia; Degenerative, Dementia Mixed
- Tested
- Transcranial Direct Current Stimulation (tDCS), 30 Hz Transcranial Alternating Current Stimulation (tACS), 50 Hz Transcr...
- Sponsor
- University of Manitoba
Who can join
- Age
- 50 to 95 years
- Sex
- All sexes
- Healthy volunteers
- Not accepted
Inclusion 5
- Minimum age: 50 years
- Maximum age: 95 years
- Study condition: Dementia; Degenerative, Dementia Mixed
- ability to read, write and speak English fluently
- MoCA score between 5 and 24
Exclusion 7
- Being diagnosed with Parkinson's disease, Parkinsonian dementia, Huntington disease, speech significant aphasia and intellectual disability, major depression/anxiety, bipolar disorder, schizophrenia or any other major mood disorder.
- Having a history of epileptic seizures or epilepsy
- Inability to adequately communicate in English
- Impaired vision or hearing severe enough to impair performance in cognitive tests
- Current substance abuse disorder
- Currently participating in another therapeutic study for dementia
- Plan to change the medication during any treatment period (5 weeks including the pre-post assessments)
Where
1 site, 1 recruiting
Riverview Health Centre
Winnipeg, Manitoba, Canada
Contact
-
Shelly Rempel-Rossum
204-789-3389 Shelly.rempelrossum@umanitoba.ca
Potential match only. Final eligibility is determined by the study team.